I Got Them All: Pathophysiology and Treatment of Overlapping Pain Conditions (207)

1:45–2:45 pm Friday, March 8

Most Complex persistent pain conditions (CPPCs) are heterogeneous with a high degree of overlap. This session will establish the degree of the overlap and explore the common pathophysiological and genetic mechanisms underlying these conditions. A mechanism-based heuristic model will be argued for treatment choices over body site specific approaches.

Molecular Pathophysiology of Overlapping Pain Conditions: The Lesson from UK Biobank

Luda Diatchenko, MD PhD

The Art and the Science of Integrative Health Approach to Management of Comorbid Pain Conditions

Inna Belfer, NIH

Multiple Pain Conditions in Quebec Pain Registry: Their Impact on Treatment Outcomes

Gabrielle Pagé, PhD

Learning Objectives:

  • Learn an evidence for similar genetic pathophysiological mechanisms underlining the high comorbidity among CPPCs and to understand which genetic variants are implicated in this shared genetic mechanism.
  • Understand the role of different complementary practices for treatment of overlapping and comorbid pain conditions, and to recognize mechanisms underlying their effects across species.
  • Examine patterns of coexistence of multiple pain conditions among patients seeking tertiary care multidisciplinary pain treatments and determine their impact on treatment response.