Opening Session: Awards & Basic Science Night (101)

3:30–5:30 pm Thursday, March 7

Sensory Disturbances in CRPS: The Robert G. Addison, MD Award Presentation

Complex regional pain syndrome (CRPS) is a debilitating and very painful condition characterized by sensory, autonomic and motor abnormalities. The condition and sensory disturbances may spread beyond the initial site of injury. The pathophysiology is poorly understood and probably involve multiple mechanisms including neuro-immune interactions, exaggerated neurogenic inflammation, changes in sympathetic function and changes in nociceptive processing. Findings regarding the involvement of changes in nociceptive processing have accumulated over the past decade. Dr. Knudsen will provide an overview of these findings and discuss the consequence of these for our understanding of CRPS.

Nociceptive Processing in Complex Regional Pain Syndrome (CRPS): The Robert G. Addison, MD Award Presentation

Lone Knudsen, MSc Psych PhD

The Neurobiology of Placebo Analgesia: How Expectation Modulates Pain

Howard L. Fields, MD PhD

Learning Objectives:

  • Describe the spread of sensory disturbances in CRPS.
  • Describe the contribution of changes in nociceptive processing to CRPS.