Most Complex persistent pain conditions (CPPCs) are heterogeneous with a high degree of overlap. This session will establish the degree of the overlap and explore the common pathophysiological and genetic mechanisms underlying these conditions. A mechanism-based heuristic model will be argued for treatment choices over body site specific approaches.
Molecular Pathophysiology of Overlapping Pain Conditions: The Lesson from UK Biobank
Luda Diatchenko, MD PhD
The Art and the Science of Integrative Health Approach to Management of Comorbid Pain Conditions
Michael Schatman, PhD
Multiple Pain Conditions in Quebec Pain Registry: Their Impact on Treatment Outcomes
Gabrielle Pagé, PhD
- Learn an evidence for similar genetic pathophysiological mechanisms underlining the high comorbidity among CPPCs and to understand which genetic variants are implicated in this shared genetic mechanism.
- Review the role of different complementary practices for treatment of overlapping and comorbid pain conditions, and to recognize mechanisms underlying their effects across species.
- Examine patterns of coexistence of multiple pain conditions among patients seeking tertiary care multidisciplinary pain treatments and determine their impact on treatment response.